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Registros recuperados : 30 | |
4. | | MACHADO, M.; RIET-CORREA, F.; PEDROSO, P.M.O.; MACÊDO, J.T.S.A. Doramectin intoxication in malnourished 15-month-old cattle. [Intoxicação por doramectina em bovinos malnutridos de 15 meses de idade.] Pesquisa Veterinaria Brasileira, 2022, Volume 42, Article e07102. OPEN ACCESS. doi: https://doi.org/10.1590/1678-5150-PVB-7102 Article history: Received 15 May 2022; Accepted 31 May 2022; Publication 29 July 2022; Date of issue 2022.
Corresponding author: Riet-Correa, F.; Animal Sciences in the Tropics (PPGCAT), Faculdade de Medicina Veterinária e Zootecnia,...Biblioteca(s): INIA Las Brujas. |
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6. | | MACHADO, M.; SCHILD, C.; PRELIASCO, M.; BALSERINI, A.; MEDEIROS, R.M.T.; BARROS, S.S.; RIET-CORREA, F. Enzootic calcinosis in sheep in Uruguay: a brief review and report of two outbreaks. [Calcinose enzoótica em ovinos no Uruguai: revisão de literatura e descrição de dois surtos.]. Pesquisa Veterinaria Brasileira, November 2020, Volume 40, Issue 11, Pages 831-836. OPEN ACCESS. Doi: http://dx.doi.org/10.1590/1678-5150-pvb-6766 Article history: Received on August 8, 2020./Accepted for publication on August 24, 2020. Part of the Doctoral Thesis of the first author.Biblioteca(s): INIA La Estanzuela. |
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7. | | CABRERA, D.; RODRIGUEZ, P.; FISCHER, L.O.; HOLZ, I.R.; PIEREZAN, H.C.; MACHADO, M.M.; RODRIGUES, T.M. Estudios de fenología en portainjertos para Prunus con potencial para el Uruguay. [Estudos de fenologia em porta-enxertos para Prunus com potencial para o Uruguai.]. [Presentación Oral-O11M2]. Módulo 2 - FISIOLOGÍA, PROPAGACIÓN Y NUEVAS TECNOLOGÍAS (Conferencia Principal y Presentaciones Orales). In: Dini, M.; Soria, J. (Eds.). Encuentro latinoamericano Prunus sin Fronteras, 8., 6-8 noviembre 2019, INIA Las Brujas, Canelones, Uruguay. Actas. Canelones (UY): INIA. p.15. (Serie Actividades de Difusión; 793) Se incluye presentación oral.Biblioteca(s): INIA Las Brujas. |
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8. | | CABRERA, D.; RODRIGUEZ, P.; FISCHER, L.O.; HOLZ, I.R.; PIEREZAN, H.C.; MACHADO, M.M.; RODRIGUES, T.M. Evaluación de diferentes fechas de raleo manual temprano en duraznero 'Opedepe' y nectarino 'Carolina'. [Avaliaçao de diferentes datas de raleio manual em pessegueiro ‘Opedepe’ e nectarina ‘Carolina’.]. [Presentación Oral-O10M2]. Módulo 2 - FISIOLOGÍA, PROPAGACIÓN Y NUEVAS TECNOLOGÍAS (Conferencia Principal y Presentaciones Orales). In: Dini, M.; Soria, J. (Eds.). Encuentro latinoamericano Prunus sin Fronteras, 8., 6-8 noviembre 2019, INIA Las Brujas, Canelones, Uruguay. Actas. Canelones (UY): INIA. p.14. (Serie Actividades de Difusión; 793) Se incluye presentación oral.Biblioteca(s): INIA Las Brujas. |
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9. | | MACHADO, M.; OLIVEIRA, L.G.S.; SCHILD, C.; BOABAID, F.; LUCAS, M.; BURONI, F.; CASTRO, M. B.; RIET-CORREA, F. Lantana camara poisoning in cattle that took refuge during a storm in a forest invaded by this plant. Toxicon, 2023, Volume 229, article 107124. https://doi.org/10.1016/j.toxicon.2023.107124 Article history: Received 8 March 2023; Received in revised form 7 April 2023; Accepted 10 April 2023; Available online 11 April 2023. -- Corresponding author: Riet-Correa, F.; Instituto Nacional de Investigación Agropecuaria, Plataforma...Biblioteca(s): INIA Las Brujas. |
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10. | | MACHADO, M.; CASTRO, M.B.; WILSON, T. M.; GONÇALVES , A. A. B.; PORTIANSKY, E.; RIET-CORREA, F.; BARROS, S. S. Poisoning by Nierembergia veitchii: Effects on vascular smooth muscle cells in the pathogenesis of enzootic calcinosis. Veterinary Pathology, 2022, Volume 59, Issue 5, pages 814-823. doi: https://doi.org/10.1177/03009858221098430 Article history: Article first published online May 19, 2022; Published online September 2022. -- Corresponding Author: Franklin Riet-Correa, Postgraduate Program in Animal Science in the Tropics, School of Veterinary Medicine and Animal...Biblioteca(s): INIA Las Brujas. |
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11. | | PISANO, J.; FISCHER, L.O.; HOLZ, I.R.; PIEREZAN, H.C.; MACHADO, M.M.; RODRIGUES, T.M. Metodología utilizada en mejoramiento genético de durazneros y nectarinos en INIA Las Brujas, Uruguay. [Presentación Poster-P32M4]. Trabajos presentados en posters. In: Dini, M.; Soria, J. (Eds.). Encuentro latinoamericano Prunus sin Fronteras, 8., 6-8 noviembre 2019, INIA Las Brujas, Canelones, Uruguay. Actas. Canelones (UY): INIA. p.62. (Serie Actividades de Difusión; 793).Biblioteca(s): INIA Las Brujas. |
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14. | | CIBILS-STEWART, X.; CALISTRO, P.; BARAIBAR, N.; GIAMBIASI, M.; GIANNITTI, F.; MACHADO, M.; SILVEIRA, C.S.; MENCHACA, A.; CAFFARENA, D.; SARAVIA, A. Escarabajo siete de oro (Astylus atromaculatus): actualización y recomendaciones en vísperas del verano 2024. Producción animal. Revista INIA Uruguay, Diciembre 2023, no.75 p.35-39. (Revista INIA; 75).Biblioteca(s): INIA Las Brujas. |
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15. | | CAMOZZI, M.G.M; SATURNINO, K. C.; MACHADO, M.R.F.; GASTAL, G.D.A.; MOREIRA, C. N.; ALVES, B. G. Cystic endometrial hyperplasia-pyometra syndrome impairs the preantral follicle reserve in domestic bitches (Canis familiaris). Reproductive Biology, December 2023, Volume 23, Issue 4, 100813. https://doi.org/10.1016/j.repbio.2023.100813 Article history: Received 19 February 2023; Received in revised form 25 September 2023; Accepted 27 September 2023; Available online 11 October 2023. -- Corresponding author: Alves, B.G.; Postgraduate Program in Animal Bioscience, Federal...Biblioteca(s): INIA Las Brujas. |
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16. | | SOUSA, A.L.V.; SOUSA, D.E.R.; CERQUEIRA, L.A.; QUEIROZ-MACHADO, C.R.R.; GIARETTA, P.R.; RIET-CORREA, F.; CASTRO, M.B.; MACHADO, M. Cestrum axillare hepatotoxicity in cattle in the Distrito Federal, Goiás and Minas Gerais. [Hepatotoxicidade do Cestrum axillare em bovinos do Distrito Federal, Goiás e Minas Gerais].. Original Article. Livestock Diseases. Pesquisa Veterinaria Brasileira. 2024, Volume 44, e07399. https://doi.org/10.1590/1678-5150-PVB-7399 -- OPEN ACCESS. Article history: Received 08 Nov 2023, Accepted 09 Dec 2023, Publication in this collection 18 Mar 2024, Date of issue 2024. -- Correspondence: Machado, M.; Graduate Program in Animal Science, Faculdade de Agronomia e Medicina...Biblioteca(s): INIA Las Brujas. |
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17. | | MACÊDO, I.L. DE; SOUSA, D.E.R. DE; SOUZA, A.D.R.; ARMIÉN, A.G.; MACHADO, M.; CASTRO, M.B. DE Fatal Africanized bee attack in captive non-human primates (Saimiri ustus and Sapajus libidinosus). Short communication. Toxicon. 2024, Volume 241, Article 107666. https://doi.org/10.1016/j.toxicon.2024.107666 Article history: Received 8 February 2024, Revised 26 February 2024, Accepted 27 February 2024, Available online 28 February 2024, Version of Record 8 March 2024. -- Correspondence: Castro, M.B.D.; Veterinary Pathology and Forensic...Biblioteca(s): INIA Las Brujas. |
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18. | | OLIVEIRA, L.G.S.; BOABAID, F.M.; KISIELIUS, V.; RASMUSSEN, L.H.; BURONI, F.; LUCAS, M.; SCHILD, C.; LÓPEZ, F.; MACHADO, M.; RIET-CORREA, F. Hemorrhagic diathesis in cattle due to consumption of Adiantopsis chlorophylla (Swartz) Fée (Pteridaceae). Toxicon: X, March 2020, Volume 5, Article number 100024. OPEN ACCESS. Doi: https://doi.org/10.1016/j.toxcx.2020.100024 Article history: Received 30 November 2019 / Revised 12 January 2020 / Accepted 13 January 2020 / Available online 23 January 2020.
Corresponding author: Franklin Riet-Correa; email: franklin.riet@pq.cnpq.br
The authors acknowledge the...Biblioteca(s): INIA Las Brujas. |
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19. | | MACHADO, M.; QUEIROZ-MACHADO, C.R.R.; GARDNER, D.R.; CASTRO, M.B.; CÂMARA, A.C.L.; PIMENTEL, L.A.; GALIZA, G.J.N.; RIET-CORREA, F. Leucaena leucocephala toxicity in Brazilian horses. Toxicon. 2024, Volume 240, Article 107655. https://doi.org/10.1016/j.toxicon.2024.107655 Article history: Received 10 January 2024; Received in revised form 16 February 2024; Accepted 18 February 2024; Available online 19 February 2024. -- Correspondence: Machado, M.; Plataforma de Investigación en Salud Animal (PSA),...Biblioteca(s): INIA Las Brujas. |
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20. | | SCHILD, C.; BOABAID F.M.; OLIVERA L.G.S.; MACHADO, M.; VILDOZA, A.; SARAVIA, A.; CUSTODIO A.; COMMAND, C.; MARTÍNEZ, A.; JAURENA, M.; DIXON, R.; RIET-CORREA, F. Osteomalacia as a result of phosphorus deficiency in beef cattle grazing subtropical native pastures in Uruguay. Journal of Veterinary Diagnostic Investigation, 2021. OPEN ACCESS. Doi: https://doi.org/10.1177/10406387211025828Biblioteca(s): INIA La Estanzuela. |
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Registros recuperados : 30 | |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
Fecha actual : |
07/06/2022 |
Actualizado : |
30/11/2022 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Circulación / Nivel : |
Internacional - -- |
Autor : |
MACHADO, M.; CASTRO, M.B.; WILSON, T. M.; GONÇALVES , A. A. B.; PORTIANSKY, E.; RIET-CORREA, F.; BARROS, S. S. |
Afiliación : |
MIZAEL MACHADO DA COSTA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; MÁRCIO B. CASTRO, University of Brasilia, Brasília, Brazil; TAIS M. WILSON, University of Brasilia, Brasília, Brazil; ALEXANDRA A. B. GONÇALVES, University of Brasilia, Brasília, Brazil; ENRIQUE L. PORTIANSKY, National University of La Plata, La Plata, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina; FRANKLIN RIET-CORREA AMARAL, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; Federal University of Bahia, Salvador, Brazil; SEVERO S. BARROS, Federal University of Santa Maria, Rio Grande do Sul, Brazil. |
Título : |
Poisoning by Nierembergia veitchii: Effects on vascular smooth muscle cells in the pathogenesis of enzootic calcinosis. |
Fecha de publicación : |
2022 |
Fuente / Imprenta : |
Veterinary Pathology, 2022, Volume 59, Issue 5, pages 814-823. doi: https://doi.org/10.1177/03009858221098430 |
ISSN : |
0300-9858 |
DOI : |
10.1177/03009858221098430 |
Idioma : |
Inglés |
Notas : |
Article history: Article first published online May 19, 2022; Published online September 2022. -- Corresponding Author: Franklin Riet-Correa, Postgraduate Program in Animal Science in the Tropics, School of Veterinary Medicine and Animal Science, Federal University of Bahia, Salvador, Bahia 40170-110, Brazil. Email: franklinrietcorrea@gmail.com -- This work was funded by National Institute of Agricultural Research (INIA) of Uruguay (Project CL 44), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Brazil, (Finance Code 001) and National University of La Plata (Project V270). A postgraduate scholarship was provided to Mizael Machado by INIA, Uruguay. |
Contenido : |
ABSTRACT - Vascular mineralization is a hallmark of enzootic calcinosis. Histopathological, ultrastructural, and immunohistochemical investigations were performed on the external carotid arteries of seven sheep naturally poisoned by Nierembergia veitchii. Histologically, moderate to marked hyperplasia of the tunica intima was observed without mineralization. The tunica media exhibited mild to severe mineralization and osteochondroid metaplasia. Sheep with enzootic calcinosis showed arterial overexpression of osteopontin and tissue-nonspecific alkaline phosphatase and immunolabeling for osteonectin and osteocalcin in both intima and media layers of the tested arteries. The main ultrastructural finding in the tunica media was a marked phenotypic change of vascular smooth muscle cells from a contractile phenotype (VSMC-C) into a synthetic phenotype (VSMC-S). In the tunica media, VSMC-S produced matrix and extracellular vesicles, forming mineralizable granules associated with arterial mineralization. VSMC-S were also present in the tunica intima, but matrix and extracellular vesicles and mineralization were not observed. The absence of matrix and extracellular vesicles in the intimal hyperplasia, even in the presence of noncollagenous bone proteins, tissue-nonspecific alkaline phosphatase, and vitamin D receptors, reinforces the hypothesis that the presence of matrix and extracellular vesicles are crucial for the development of vascular mineralization in enzootic calcinosis. It is proposed that the two different VSMC-S phenotypes in calcinosis are due to the expression of at least two genetically different types of these cells induced by the action of 1,25(OH)2D3. © The Author(s) 2022. MenosABSTRACT - Vascular mineralization is a hallmark of enzootic calcinosis. Histopathological, ultrastructural, and immunohistochemical investigations were performed on the external carotid arteries of seven sheep naturally poisoned by Nierembergia veitchii. Histologically, moderate to marked hyperplasia of the tunica intima was observed without mineralization. The tunica media exhibited mild to severe mineralization and osteochondroid metaplasia. Sheep with enzootic calcinosis showed arterial overexpression of osteopontin and tissue-nonspecific alkaline phosphatase and immunolabeling for osteonectin and osteocalcin in both intima and media layers of the tested arteries. The main ultrastructural finding in the tunica media was a marked phenotypic change of vascular smooth muscle cells from a contractile phenotype (VSMC-C) into a synthetic phenotype (VSMC-S). In the tunica media, VSMC-S produced matrix and extracellular vesicles, forming mineralizable granules associated with arterial mineralization. VSMC-S were also present in the tunica intima, but matrix and extracellular vesicles and mineralization were not observed. The absence of matrix and extracellular vesicles in the intimal hyperplasia, even in the presence of noncollagenous bone proteins, tissue-nonspecific alkaline phosphatase, and vitamin D receptors, reinforces the hypothesis that the presence of matrix and extracellular vesicles are crucial for the development of vascular mineralization in enzootic calcinosis. It ... Presentar Todo |
Palabras claves : |
Arterial mineralization; Arteries; Enzootic calcinosis; Exosomes; Pathogenesis; PLATAFORMA DE SALUD ANIMAL; Toxicity; Vascular smooth muscle cells. |
Asunto categoría : |
L50 Fisiología y bioquímica animal |
Marc : |
LEADER 03391nam a2200313 a 4500 001 1063233 005 2022-11-30 008 2022 bl uuuu u01u1 u #d 022 $a0300-9858 024 7 $a10.1177/03009858221098430$2DOI 100 1 $aMACHADO, M. 245 $aPoisoning by Nierembergia veitchii$bEffects on vascular smooth muscle cells in the pathogenesis of enzootic calcinosis.$h[electronic resource] 260 $aVeterinary Pathology, 2022, Volume 59, Issue 5, pages 814-823. doi: https://doi.org/10.1177/03009858221098430$c1177 500 $aArticle history: Article first published online May 19, 2022; Published online September 2022. -- Corresponding Author: Franklin Riet-Correa, Postgraduate Program in Animal Science in the Tropics, School of Veterinary Medicine and Animal Science, Federal University of Bahia, Salvador, Bahia 40170-110, Brazil. Email: franklinrietcorrea@gmail.com -- This work was funded by National Institute of Agricultural Research (INIA) of Uruguay (Project CL 44), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Brazil, (Finance Code 001) and National University of La Plata (Project V270). A postgraduate scholarship was provided to Mizael Machado by INIA, Uruguay. 520 $aABSTRACT - Vascular mineralization is a hallmark of enzootic calcinosis. Histopathological, ultrastructural, and immunohistochemical investigations were performed on the external carotid arteries of seven sheep naturally poisoned by Nierembergia veitchii. Histologically, moderate to marked hyperplasia of the tunica intima was observed without mineralization. The tunica media exhibited mild to severe mineralization and osteochondroid metaplasia. Sheep with enzootic calcinosis showed arterial overexpression of osteopontin and tissue-nonspecific alkaline phosphatase and immunolabeling for osteonectin and osteocalcin in both intima and media layers of the tested arteries. The main ultrastructural finding in the tunica media was a marked phenotypic change of vascular smooth muscle cells from a contractile phenotype (VSMC-C) into a synthetic phenotype (VSMC-S). In the tunica media, VSMC-S produced matrix and extracellular vesicles, forming mineralizable granules associated with arterial mineralization. VSMC-S were also present in the tunica intima, but matrix and extracellular vesicles and mineralization were not observed. The absence of matrix and extracellular vesicles in the intimal hyperplasia, even in the presence of noncollagenous bone proteins, tissue-nonspecific alkaline phosphatase, and vitamin D receptors, reinforces the hypothesis that the presence of matrix and extracellular vesicles are crucial for the development of vascular mineralization in enzootic calcinosis. It is proposed that the two different VSMC-S phenotypes in calcinosis are due to the expression of at least two genetically different types of these cells induced by the action of 1,25(OH)2D3. © The Author(s) 2022. 653 $aArterial mineralization 653 $aArteries 653 $aEnzootic calcinosis 653 $aExosomes 653 $aPathogenesis 653 $aPLATAFORMA DE SALUD ANIMAL 653 $aToxicity 653 $aVascular smooth muscle cells 700 1 $aCASTRO, M.B. 700 1 $aWILSON, T. M. 700 1 $aGONÇALVES , A. A. B. 700 1 $aPORTIANSKY, E. 700 1 $aRIET-CORREA, F. 700 1 $aBARROS, S. S.
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